Reading the news these days feels like riding a roller-coaster. In addition to massive inflation and military conflicts, we are experiencing another public health crisis, even though some of us are still recovering from its predecessor. Monkeypox is a previously uncommon zoonotic disease caused by the monkeypox virus, an Orthopoxvirus. While we have known of this virus for years, its impact had mostly been limited, with the person-to-person transmission not reported anywhere outside Africa. However, this year, transmission occurs widely in the United States. Please keep reading to discover the most up-to-date billing and reimbursement guidelines for monkeypox-related procedures.